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1803 Friedrich Sertuerner of Paderborn, Germany discovers the active ingredient of opium by dissolving it in acid then neutralizing it with ammonia. The result: alkaloids- Principium somniferum or morphine. This will have been the very first plant alkaloid ever isolated and established off a firestorm of investigation into plant alkaloids. https://enrollbookmarks.com/story14831454/not-known-facts-about-sex-%C3%A2u-m%E1%BB%B9

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