Many receptor-mediated occasions present the phenomenon of desensitization, meaning that ongoing or recurring administration of the drug makes a progressively lesser outcome. Among the sophisticated mechanisms concerned are conversion in the receptors into a refractory (unresponsive) state in the presence of an agonist, to ensure activation can not occur, or https://mylesyekqv.wikipresses.com/4309465/the_best_side_of_vytápění