Ketamine can have extraordinary advantageous effects in patients with quite badly controlled pain, especially while in the presence of preexisting patient problems like chronic pain, opioid tolerance, opioid-induced hyperalgesia, and opioid use disorder. Esketamine (Spravato), among the list of forms of racemic ketamine, was approved in 2019 for particular types https://piersr000shv9.wiki-cms.com/user