There is a release of norepinephrine in the descending inhibitory bulbospinal neurons that binds to alpha-two-receptors during the dorsal horn to lessen afferent suffering transmission and produce analgesia. Consequently, prescription drugs like clonidine that goal alpha-2 receptors can impact the transmission of pain. Clonidine is distributed in breast milk; https://kirstent738lbu2.ageeksblog.com/profile